Ocular Pharmacokinetics of Dorzolamide and Brinzolamide After Single and Multiple Topical Dosing: Implications for Effects on Ocular Blood Flow

Ophthalmic carbonic anhydrase inhibitors have been shown to improve retinal and optic nerve blood flow. However, the relative tissue distributions of commercially available carbonic anhydrase inhibitors to the optic nerve are not known. The objective of this study was to compare the ocular pharmacok...

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Bibliographic Details
Main Authors: Kadam, Rajendra S., Jadhav, Gajanan, Ogidigben, Miller, Kompella, Uday B.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2011
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164276/
https://ncbi.nlm.nih.gov/pubmed/21673129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.040055
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