Structure and Dynamics of Oligomeric Intermediates in β(2)-Microglobulin Self-Assembly

β(2)-Microglobulin is a 99-residue protein with a propensity to form amyloid-like fibrils in vitro which exhibit distinct morphologies dependent on the solution conditions employed. Here we have used ion mobility spectrometry-mass spectrometry to characterize the oligomeric species detected during t...

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Hlavní autoři: Smith, David P., Woods, Lucy A., Radford, Sheena E., Ashcroft, Alison E.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2011
Témata:
Protein
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164137/
https://ncbi.nlm.nih.gov/pubmed/21889462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.07.023
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