Farnesoid X receptor represses hepatic human APOA gene expression

High plasma concentrations of lipoprotein(a) [Lp(a), which is encoded by the APOA gene] increase an individual’s risk of developing diseases, such as coronary artery diseases, restenosis, and stroke. Unfortunately, increased Lp(a) levels are minimally influenced by dietary changes or drug treatment....

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Autores principales: Chennamsetty, Indumathi, Claudel, Thierry, Kostner, Karam M., Baghdasaryan, Anna, Kratky, Dagmar, Levak-Frank, Sanja, Frank, Sasa, Gonzalez, Frank J., Trauner, Michael, Kostner, Gert M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163948/
https://ncbi.nlm.nih.gov/pubmed/21804189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45277
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