Studies in mice, hamsters, and rats demonstrate that repression of hepatic apoA-I expression by taurocholic acid in mice is not mediated by the farnesoid-X-receptor

It is claimed that apoA-I expression is repressed in mice by cholic acid (CA) and its taurine conjugate, taurocholic acid (TCA) via farnesoid X receptor (FXR) activation. We measured apoA-I expression in mice, hamsters, and rats treated with highly potent and selective synthetic FXR agonists or with...

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Detalhes bibliográficos
Main Authors: Gardès, Christophe, Blum, Denise, Bleicher, Konrad, Chaput, Evelyne, Ebeling, Martin, Hartman, Peter, Handschin, Corinne, Richter, Hans, Benson, G. Martin
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090240/
https://ncbi.nlm.nih.gov/pubmed/21464203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M012542
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