The HSP90 Molecular Chaperone Cycle Regulates Cyclical Transcriptional Dynamics of the Glucocorticoid Receptor and Its Coregulatory Molecules CBP/p300 During Ultradian Ligand Treatment

Glucocorticoid (GC) hormones are secreted from the adrenal gland in a characteristic pulsatile pattern. This ultradian secretory activity exhibits remarkable plasticity, with distinct changes in response to both physiological and stressful stimuli in humans and experimental animals. It is therefore...

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Autores principales: Conway-Campbell, Becky L., George, Charlotte L., Pooley, John R., Knight, David M., Norman, Michael R., Hager, Gordon L., Lightman, Stafford L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2011
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163797/
https://ncbi.nlm.nih.gov/pubmed/21511880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0073
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