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Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription

Studies on glucocorticoid receptor (GR) action typically assess gene responses by long-term stimulation with synthetic hormones. As corticosteroids are released from adrenal glands in a circadian and high-frequency (ultradian) mode, such treatments may not provide an accurate assessment of physiolog...

詳細記述

保存先:
書誌詳細
出版年:Nat Cell Biol
主要な著者: Stavreva, Diana A., Wiench, Malgorzata, John, Sam, Conway-Campbell, Becky L., McKenna, Mervyn A., Pooley, John R., Johnson, Thomas A., Voss, Ty C., Lightman, Stafford L., Hager, Gordon L.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711162/
https://ncbi.nlm.nih.gov/pubmed/19684579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1922
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