Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation

Stat5 is activated by multiple receptors of hematopoietic cytokines. To study its role during hematopoiesis, we have generated primary chicken myeloblasts expressing different dominant-negative (dn) alleles of Stat5. This caused a striking inability to generate mature cells, due to massive apoptosis...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Kieslinger, Matthias, Woldman, Irina, Moriggl, Richard, Hofmann, Johannes, Marine, Jean-Christophe, Ihle, James N., Beug, Hartmut, Decker, Thomas
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 2000
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316353/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10652277/
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