Targeting of N-CoR and histone deacetylase 3 by the oncoprotein v-ErbA yields a chromatin infrastructure-dependent transcriptional repression pathway

Transcriptional repression by nuclear hormone receptors is thought to result from a unison of targeting chromatin modification and disabling the basal transcriptional machinery. We used Xenopus oocytes to compare silencing effected by the thyroid hormone receptor (TR) and its mutated version, the on...

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Main Authors: Urnov, Fyodor D., Yee, Janet, Sachs, Laurent, Collingwood, Trevor N., Bauer, Anton, Beug, Hartmut, Shi, Yun-Bo, Wolffe, Alan P.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2000
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC306612/
https://ncbi.nlm.nih.gov/pubmed/10921888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.15.4074
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