Loading...

Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-β and promotes tumor invasion and angiogenesis

We have uncovered a novel functional relationship between the hyaluronan receptor CD44, the matrix metalloproteinase-9 (MMP-9) and the multifunctional cytokine TGF-β in the control of tumor-associated tissue remodeling. CD44 provides a cell surface docking receptor for proteolytically active MMP-9 a...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Yu, Qin, Stamenkovic, Ivan
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC316345/
https://ncbi.nlm.nih.gov/pubmed/10652271
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!