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Osteopontin is proteolytically processed by matrix metalloproteinase 9()

Osteopontin is robustly upregulated following myocardial infarction (MI), which suggests that it has an important role in post-MI remodeling of the left ventricle (LV). Osteopontin deletion results in increased LV dilation and worsened cardiac function. Thus, osteopontin exerts protective effects po...

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Detalhes bibliográficos
Publicado no:Can J Physiol Pharmacol
Main Authors: Lindsey, Merry L., Zouein, Fouad A., Tian, Yuan, Iyer, Rugmani Padmanabhan, de Castro Brás, Lisandra E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764993/
https://ncbi.nlm.nih.gov/pubmed/26176332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/cjpp-2015-0019
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