An essential role in liver development for transcription factor XBP-1

XBP-1 is a CREB/ATF family transcription factor highly expressed in hepatocellular carcinomas. Here we report that XBP-1 is essential for liver growth. Mice lacking XBP-1 displayed hypoplastic fetal livers, whose reduced hematopoiesis resulted in death from anemia. Nevertheless, XBP-1-deficient hema...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Reimold, Andreas M., Etkin, Amit, Clauss, Isabelle, Perkins, Andrew, Friend, Daniel S., Zhang, John, Horton, Heidi F., Scott, Andrew, Orkin, Stuart H., Byrne, Michael C., Grusby, Michael J., Glimcher, Laurie H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2000
Onderwerpen:
Research Communication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC316338/
https://ncbi.nlm.nih.gov/pubmed/10652269
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items