An essential role in liver development for transcription factor XBP-1

XBP-1 is a CREB/ATF family transcription factor highly expressed in hepatocellular carcinomas. Here we report that XBP-1 is essential for liver growth. Mice lacking XBP-1 displayed hypoplastic fetal livers, whose reduced hematopoiesis resulted in death from anemia. Nevertheless, XBP-1-deficient hema...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Reimold, Andreas M., Etkin, Amit, Clauss, Isabelle, Perkins, Andrew, Friend, Daniel S., Zhang, John, Horton, Heidi F., Scott, Andrew, Orkin, Stuart H., Byrne, Michael C., Grusby, Michael J., Glimcher, Laurie H.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2000
Matèries:
Research Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC316338/
https://ncbi.nlm.nih.gov/pubmed/10652269
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars