Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway

Transcriptional repression mediated by corepressors N-CoR and SMRT is a critical function of nuclear hormone receptors, and is dysregulated in human myeloid leukemias. At the present time, these corepressors are thought to act exclusively through an mSin3/HDAC1 complex. Surprisingly, however, numero...

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Main Authors: Huang, Eric Y., Zhang, Jinsong, Miska, Eric A., Guenther, Matthew G., Kouzarides, Tony, Lazar, Mitchell A.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2000
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Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC316335/
https://ncbi.nlm.nih.gov/pubmed/10640275
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