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Circadian CLOCK-mediated Regulation of Target-tissue Sensitivity to Glucocorticoids: Implications for Cardiometabolic Diseases
Glucocorticoids, the end-products of the hypothalamic-pituitary-adrenal (HPA) axis, influence the functions of virtually all organs and tissues through the nuclear glucocorticoid receptor (GR). Circulating levels of glucocorticoids fluctuate naturally in a circadian fashion under the strong influenc...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3163295/ https://ncbi.nlm.nih.gov/pubmed/21164265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000321232 |
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