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Circadian CLOCK-mediated Regulation of Target-tissue Sensitivity to Glucocorticoids: Implications for Cardiometabolic Diseases

Glucocorticoids, the end-products of the hypothalamic-pituitary-adrenal (HPA) axis, influence the functions of virtually all organs and tissues through the nuclear glucocorticoid receptor (GR). Circulating levels of glucocorticoids fluctuate naturally in a circadian fashion under the strong influenc...

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Bibliografische gegevens
Hoofdauteurs: Kino, Tomoshige, Chrousos, George P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163295/
https://ncbi.nlm.nih.gov/pubmed/21164265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000321232
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