Peripheral CLOCK Regulates Target-Tissue Glucocorticoid Receptor Transcriptional Activity in a Circadian Fashion in Man

CONTEXT AND OBJECTIVE: Circulating cortisol fluctuates diurnally under the control of the “master” circadian CLOCK, while the peripheral “slave” counterpart of the latter regulates the transcriptional activity of the glucocorticoid receptor (GR) at local glucocorticoid target tissues through acetyla...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Charmandari, Evangelia, Chrousos, George P., Lambrou, George I., Pavlaki, Aikaterini, Koide, Hisashi, Ng, Sinnie Sin Man, Kino, Tomoshige
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182238/
https://ncbi.nlm.nih.gov/pubmed/21980503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025612
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky