Peripheral CLOCK Regulates Target-Tissue Glucocorticoid Receptor Transcriptional Activity in a Circadian Fashion in Man

CONTEXT AND OBJECTIVE: Circulating cortisol fluctuates diurnally under the control of the “master” circadian CLOCK, while the peripheral “slave” counterpart of the latter regulates the transcriptional activity of the glucocorticoid receptor (GR) at local glucocorticoid target tissues through acetyla...

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Bibliografische gegevens
Hoofdauteurs: Charmandari, Evangelia, Chrousos, George P., Lambrou, George I., Pavlaki, Aikaterini, Koide, Hisashi, Ng, Sinnie Sin Man, Kino, Tomoshige
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2011
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182238/
https://ncbi.nlm.nih.gov/pubmed/21980503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025612
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