Loss of intestinal GATA4 prevents diet-induced obesity and promotes insulin sensitivity in mice

Transcriptional regulation of small intestinal gene expression controls plasma total cholesterol (TC) and triglyceride (TG) levels, which are major determinants of metabolic diseases. GATA4, a zinc finger domain transcription factor, is critical for jejunal identity, and intestinal GATA4 deficiency...

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Autores principales: Patankar, Jay V., Chandak, Prakash G., Obrowsky, Sascha, Pfeifer, Thomas, Diwoky, Clemens, Uellen, Andreas, Sattler, Wolfgang, Stollberger, Rudolf, Hoefler, Gerald, Heinemann, Akos, Battle, Michele, Duncan, Stephen, Kratky, Dagmar, Levak-Frank, Sanja
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2011
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163292/
https://ncbi.nlm.nih.gov/pubmed/21177287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00457.2010
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