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Poly(I:C) promotes TNFα/TNFR1-dependent oligodendrocyte death in mixed glial cultures
BACKGROUND: Activation of glial cells via toll-like receptors (TLRs) and other intracellular pathogen recognition receptors promotes the release of potentially toxic acute phase reactants such as TNFα and nitric oxide into the extracellular space. As such, prolonged glial activation, as is thought t...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3162898/ https://ncbi.nlm.nih.gov/pubmed/21812954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-89 |
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