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Poly(I:C) promotes TNFα/TNFR1-dependent oligodendrocyte death in mixed glial cultures

BACKGROUND: Activation of glial cells via toll-like receptors (TLRs) and other intracellular pathogen recognition receptors promotes the release of potentially toxic acute phase reactants such as TNFα and nitric oxide into the extracellular space. As such, prolonged glial activation, as is thought t...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Steelman, Andrew J, Li, Jianrong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162898/
https://ncbi.nlm.nih.gov/pubmed/21812954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-89
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