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Poly(I:C) promotes TNFα/TNFR1-dependent oligodendrocyte death in mixed glial cultures

BACKGROUND: Activation of glial cells via toll-like receptors (TLRs) and other intracellular pathogen recognition receptors promotes the release of potentially toxic acute phase reactants such as TNFα and nitric oxide into the extracellular space. As such, prolonged glial activation, as is thought t...

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Bibliografische gegevens
Hoofdauteurs: Steelman, Andrew J, Li, Jianrong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162898/
https://ncbi.nlm.nih.gov/pubmed/21812954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-89
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