C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress

BACKGROUND: TDP-43 proteinopathies are characterized by loss of nuclear TDP-43 expression and formation of C-terminal TDP-43 fragmentation and accumulation in the cytoplasm. Recent studies have shown that TDP-43 can accumulate in RNA stress granules (SGs) in response to cell stresses and this could...

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Detalhes bibliográficos
Main Authors: Meyerowitz, Jodi, Parker, Sarah J, Vella, Laura J, Ng, Dominic CH, Price, Katherine A, Liddell, Jeffrey R, Caragounis, Aphrodite, Li, Qiao-Xin, Masters, Colin L, Nonaka, Takashi, Hasegawa, Masato, Bogoyevitch, Marie A, Kanninen, Katja M, Crouch, Peter J, White, Anthony R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162576/
https://ncbi.nlm.nih.gov/pubmed/21819629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-57
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