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Stimulating the Substrate Folding Activity of a Single Ring GroEL Variant by Modulating the Cochaperonin GroES

In mediating protein folding, chaperonin GroEL and cochaperonin GroES form an enclosed chamber for substrate proteins in an ATP-dependent manner. The essential role of the double ring assembly of GroEL is demonstrated by the functional deficiency of the single ring GroEL(SR). The GroEL(SR)-GroES is...

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Detalhes bibliográficos
Main Authors: Illingworth, Melissa, Ramsey, Andrew, Zheng, Zhida, Chen, Lingling
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162399/
https://ncbi.nlm.nih.gov/pubmed/21757689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.255935
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