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Single-molecule Observation of Protein Folding in Symmetric GroEL-(GroES)(2) Complexes

The chaperonin, GroEL, is an essential molecular chaperone that mediates protein folding together with its cofactor, GroES, in Escherichia coli. It is widely believed that the two rings of GroEL alternate between the folding active state coupled to GroES binding during the reaction cycle. In other w...

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Bibliografiske detaljer
Main Authors: Takei, Yodai, Iizuka, Ryo, Ueno, Taro, Funatsu, Takashi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510812/
https://ncbi.nlm.nih.gov/pubmed/23048033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.398628
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