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Single-molecule Observation of Protein Folding in Symmetric GroEL-(GroES)(2) Complexes
The chaperonin, GroEL, is an essential molecular chaperone that mediates protein folding together with its cofactor, GroES, in Escherichia coli. It is widely believed that the two rings of GroEL alternate between the folding active state coupled to GroES binding during the reaction cycle. In other w...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3510812/ https://ncbi.nlm.nih.gov/pubmed/23048033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.398628 |
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