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Single-molecule Observation of Protein Folding in Symmetric GroEL-(GroES)(2) Complexes

The chaperonin, GroEL, is an essential molecular chaperone that mediates protein folding together with its cofactor, GroES, in Escherichia coli. It is widely believed that the two rings of GroEL alternate between the folding active state coupled to GroES binding during the reaction cycle. In other w...

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Autors principals: Takei, Yodai, Iizuka, Ryo, Ueno, Taro, Funatsu, Takashi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510812/
https://ncbi.nlm.nih.gov/pubmed/23048033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.398628
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