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Single-molecule Observation of Protein Folding in Symmetric GroEL-(GroES)(2) Complexes

The chaperonin, GroEL, is an essential molecular chaperone that mediates protein folding together with its cofactor, GroES, in Escherichia coli. It is widely believed that the two rings of GroEL alternate between the folding active state coupled to GroES binding during the reaction cycle. In other w...

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Main Authors: Takei, Yodai, Iizuka, Ryo, Ueno, Taro, Funatsu, Takashi
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510812/
https://ncbi.nlm.nih.gov/pubmed/23048033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.398628
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