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Toll-like Receptor 4 (TLR4) Is Essential for Hsp70-like Protein 1 (HSP70L1) to Activate Dendritic Cells and Induce Th1 Response

Toll-like receptors (TLRs) play important roles in initiation of innate and adaptive immune responses. Emerging evidence suggests that TLR agonists can serve as potential adjuvant for vaccination. Heat shock proteins (HSPs), functionally serving as TLR4 agonists, have been proposed to act as Th1 adj...

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Detalhes bibliográficos
Main Authors: Fang, Hongliang, Wu, Yanfeng, Huang, Xiaohui, Wang, Wenying, Ang, Bing, Cao, Xuetao, Wan, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162398/
https://ncbi.nlm.nih.gov/pubmed/21730052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.266528
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