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Efficient induction of a Her2-specific anti-tumor response by dendritic cells pulsed with a Hsp70L1–Her2(341–456) fusion protein

Heat shock proteins (HSPs) have been shown to interact with antigen-presenting cells (APCs), especially dendritic cells (DCs). HSPs act as potent adjuvants, inducing a Th1 response, as well as antigen-specific CD8(+) cytotoxic T lymphocytes (CTL) via cross-presentation. Our previous work has demonst...

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Detalhes bibliográficos
Main Authors: Fu, Qiang, Wu, Yanfeng, Yan, Fang, Wang, Ning, Wang, Wenying, Cao, Xuetao, Wang, Yajie, Wan, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012883/
https://ncbi.nlm.nih.gov/pubmed/21785448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2011.21
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