A murine-ES like state facilitates transgenesis and homologous recombination in human pluripotent stem cells

Murine embryonic stem cells have been shown to exist in two functionally distinct pluripotent states, embryonic stem cells (ES cell)- and epiblast stem cells (EpiSCs), which are defined by the culture growth factor conditions. Human ES cells appear to exist in an epiblast-like state, which in compar...

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Autores principales: Buecker, Christa, Chen, Hsu-Hsin, Polo, Jose, Daheron, Laurence, Bu, Lei, Barakat, Tahsin Stefan, Okwieka, Patricia, Porter, Andrew, Gribnau, Joost, Hochedlinger, Konrad, Geijsen, Niels
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162213/
https://ncbi.nlm.nih.gov/pubmed/20569691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.05.003
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