A murine-ES like state facilitates transgenesis and homologous recombination in human pluripotent stem cells

Murine embryonic stem cells have been shown to exist in two functionally distinct pluripotent states, embryonic stem cells (ES cell)- and epiblast stem cells (EpiSCs), which are defined by the culture growth factor conditions. Human ES cells appear to exist in an epiblast-like state, which in compar...

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Detalhes bibliográficos
Main Authors: Buecker, Christa, Chen, Hsu-Hsin, Polo, Jose, Daheron, Laurence, Bu, Lei, Barakat, Tahsin Stefan, Okwieka, Patricia, Porter, Andrew, Gribnau, Joost, Hochedlinger, Konrad, Geijsen, Niels
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162213/
https://ncbi.nlm.nih.gov/pubmed/20569691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.05.003
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