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Lowe Syndrome Protein OCRL1 Supports Maturation of Polarized Epithelial Cells
Mutations in the inositol polyphosphate 5-phosphatase OCRL1 cause Lowe Syndrome, leading to cataracts, mental retardation and renal failure. We noted that cell types affected in Lowe Syndrome are highly polarized, and therefore we studied OCRL1 in epithelial cells as they mature from isolated indivi...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3162020/ https://ncbi.nlm.nih.gov/pubmed/21901156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024044 |
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