Mixed-Affinity Binding in Humans with 18-kDa Translocator Protein Ligands

(11)C-PBR28 PET can detect the 18-kDa translocator protein (TSPO) expressed within macrophages. However, quantitative evaluation of the signal in brain tissue from donors with multiple sclerosis (MS) shows that PBR28 binds the TSPO with high affinity (binding affinity [K(i)], ~4 nM), low affinity (K...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Owen, David R.J., Gunn, Roger N., Rabiner, Eugenii A., Bennacef, Idriss, Fujita, Masahiro, Kreisl, William C., Innis, Robert B., Pike, Victor W., Reynolds, Richard, Matthews, Paul M., Parker, Christine A.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161826/
https://ncbi.nlm.nih.gov/pubmed/21149489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.110.079459
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars