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DNA-induced narrowing of the gyrase N-gate coordinates T-segment capture and strand passage
DNA gyrase introduces negative supercoils into DNA in an ATP-dependent reaction. DNA supercoiling is catalyzed by a strand-passage mechanism, in which a T-segment of DNA is passed through the gap in a transiently cleaved G-segment. Strand passage requires the coordinated closing and opening of three...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3161603/ https://ncbi.nlm.nih.gov/pubmed/21817063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102100108 |
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