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Biosynthesis of the Antimicrobial Peptide Epilancin 15X and Its N-terminal Lactate

Lantibiotics are ribosomally synthesized and posttranslationally modified antimicrobial peptides. The recently discovered lantibiotic epilancin 15X produced by Staphylococcus epidermidis 15X154 contains an unusual N-terminal lactate group. To understand its biosynthesis, the epilancin 15X biosynthet...

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Bibliographic Details
Main Authors: Velásquez, Juan E., Zhang, Xingang, van der Donk, Wilfred
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161514/
https://ncbi.nlm.nih.gov/pubmed/21802007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.05.007
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