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Comparison of the Pharmacokinetics of Different Analogs of (11)C-Labeled TZTP for Imaging Muscarinic M2 Receptors with PET

INTRODUCTION: The only radiotracer available for the selective imaging of muscarinic M2 receptors in vivo is 3-(3-{3-[(18)F]fluoropropyl)thio}-1,2,5-thiadiazol-4-yl)-1,2,5,6-tetrahydro-1-methylpyridine) ([(18)F]FP-TZTP). We have prepared and labeled FP-TZTP and two other TZTP derivatives with (11)C...

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Detalhes bibliográficos
Main Authors: Reid, Alicia E., Ding, Yu-Shin, Eckelman, William C., Logan, Jean, Alexoff, David, Shea, Colleen, Xu, Youwen, Fowler, Joanna S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161448/
https://ncbi.nlm.nih.gov/pubmed/18355684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2008.01.001
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