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Early limited nitrosamine exposures exacerbate high fat diet-mediated type 2 diabetes and neurodegeneration

BACKGROUND: Type 2 diabetes mellitus (T2DM) and several types of neurodegeneration, including Alzheimer's, are linked to insulin-resistance, and chronic high dietary fat intake causes T2DM with mild neurodegeneration. Intra-cerebral Streptozotocin, a nitrosamine-related compound, causes neurode...

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Detalhes bibliográficos
Main Authors: Tong, Ming, Longato, Lisa, de la Monte, Suzanne M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161394/
https://ncbi.nlm.nih.gov/pubmed/20302640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6823-10-4
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