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MECHANISMS OF NITROSAMINE–MEDIATED NEURODEGENERATION: POTENTIAL RELEVANCE TO SPORADIC ALZHEIMER’S DISEASE
BACKGROUND: Streptozotocin (STZ) is a nitrosamine-related compound that causes Alzheimer disease (AD)-type neurodegeneration with cognitive impairment, brain insulin resistance, and brain insulin deficiency. Nitrosamines and STZ mediate their adverse effects by causing DNA damage, oxidative stress,...
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| Publicado no: | J Alzheimers Dis |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4550318/ https://ncbi.nlm.nih.gov/pubmed/19542621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2009-1098 |
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