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MECHANISMS OF NITROSAMINE–MEDIATED NEURODEGENERATION: POTENTIAL RELEVANCE TO SPORADIC ALZHEIMER’S DISEASE

BACKGROUND: Streptozotocin (STZ) is a nitrosamine-related compound that causes Alzheimer disease (AD)-type neurodegeneration with cognitive impairment, brain insulin resistance, and brain insulin deficiency. Nitrosamines and STZ mediate their adverse effects by causing DNA damage, oxidative stress,...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Alzheimers Dis
Main Authors: de la Monte, Suzanne M., Tong, Ming
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550318/
https://ncbi.nlm.nih.gov/pubmed/19542621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2009-1098
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