Therapeutic Impact of Leptin on Diabetes, Diabetic Complications, and Longevity in Insulin-Deficient Diabetic Mice

OBJECTIVE: The aim of the current study was to evaluate the long-term effects of leptin on glucose metabolism, diabetes complications, and life span in an insulin-dependent diabetes model, the Akita mouse. RESEARCH DESIGN AND METHODS: We cross-mated Akita mice with leptin-expressing transgenic (LepT...

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Autors principals: Naito, Masaki, Fujikura, Junji, Ebihara, Ken, Miyanaga, Fumiko, Yokoi, Hideki, Kusakabe, Toru, Yamamoto, Yuji, Son, Cheol, Mukoyama, Masashi, Hosoda, Kiminori, Nakao, Kazuwa
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2011
Matèries:
Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161331/
https://ncbi.nlm.nih.gov/pubmed/21810600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1795
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