Cyclic AMP induces apoptosis in multiple myeloma cells and inhibits tumor development in a mouse myeloma model

BACKGROUND: Multiple myeloma is an incurable disease requiring the development of effective therapies which can be used clinically. We have elucidated the potential for manipulating the cAMP signaling pathway as a target for inhibiting the growth of multiple myeloma cells. METHODS: As a model system...

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Hauptverfasser: Follin-Arbelet, Virginie, Hofgaard, Peter O, Hauglin, Harald, Naderi, Soheil, Sundan, Anders, Blomhoff, Rune, Bogen, Bjarne, Blomhoff, Heidi K
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161033/
https://ncbi.nlm.nih.gov/pubmed/21767374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-301
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