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Tracking Early Autoimmune Disease by Bioluminescent Imaging of NF-κB Activation Reveals Pathology in Multiple Organ Systems

It is desirable to have an early and sensitive detection marker of autoimmune disease in intact animals. Nuclear factor (NF)-κB is a transcription factor that is associated with inflammatory responses and immune disorders. Previously, we demonstrated that so-called idiotypic-driven T–B cell collabor...

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Detalhes bibliográficos
Main Authors: Zangani, Michael, Carlsen, Harald, Kielland, Anders, Os, Audun, Hauglin, Harald, Blomhoff, Rune, Munthe, Ludvig A., Bogen, Bjarne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671367/
https://ncbi.nlm.nih.gov/pubmed/19286564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080700
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