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Statistical issues in the design and analysis of expertise-based randomized clinical trials

In order to avoid certain difficulties with the conventional randomized clinical trial design, the expertise-based design has been proposed as an alternative. In the expertise-based design, patients are randomized to clinicians (e.g. surgeons), who then treat all their patients with their preferred...

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Bibliographic Details
Main Authors: Walter, S. D., Ismaila, A. S., Devereaux, P. J.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160982/
https://ncbi.nlm.nih.gov/pubmed/18837074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.3448
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