Critical Role of PI3K/Akt/GSK3β in Motoneuron Specification from Human Neural Stem Cells in Response to FGF2 and EGF

Fibroblast growth factor (FGF) and epidermal growth factor (EGF) are critical for the development of the nervous system. We previously discovered that FGF2 and EGF had opposite effects on motor neuron differentiation from human fetal neural stem cells (hNSCs), but the underlying mechanisms remain un...

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Bibliografiske detaljer
Main Authors: Ojeda, Luis, Gao, Junling, Hooten, Kristopher G., Wang, Enyin, Thonhoff, Jason R., Dunn, Tiffany J., Gao, Tianyan, Wu, Ping
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160859/
https://ncbi.nlm.nih.gov/pubmed/21887250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023414
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