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Linking RNA Polymerase Backtracking to Genome Instability
Frequent co-directional collisions between the replisome and RNA polymerase (RNAP) are inevitable because the rate of replication is much faster than that of transcription. Here we show that the outcome of such collisions depends on the productive state of transcription elongation complexes (ECs). C...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3160732/ https://ncbi.nlm.nih.gov/pubmed/21854980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.07.034 |
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