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RNA Polymerase Backtracking in Gene Regulation and Genome Instability
RNA polymerase is a ratchet machine that oscillates between productive and backtracked states at numerous DNA positions. The amount of backtracking (reversible sliding of the enzyme along DNA and RNA) varies from one to many nucleotides. Since its first description 15 years ago, backtracking has bee...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3815583/ https://ncbi.nlm.nih.gov/pubmed/22726433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.06.003 |
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