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Phosphorylation of p27Kip1 by JAK2 directly links cytokine receptor signaling to cell cycle control
Janus kinase 2 (JAK2) couples ligand activation of cell surface cytokine receptors to the regulation of cellular functions including cell cycle progression, differentiation and apoptosis. It thereby coordinates biological programs such as development and hematopoiesis. Unscheduled activation of JAK2...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3160490/ https://ncbi.nlm.nih.gov/pubmed/21423214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.68 |
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