HIV-1 Nef Induces Proinflammatory State in Macrophages through Its Acidic Cluster Domain: Involvement of TNF Alpha Receptor Associated Factor 2

BACKGROUND: HIV-1 Nef is a virulence factor that plays multiple roles during HIV replication. Recently, it has been described that Nef intersects the CD40 signalling in macrophages, leading to modification in the pattern of secreted factors that appear able to recruit, activate and render T lymphocy...

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Hlavní autoři: Mangino, Giorgio, Percario, Zulema A., Fiorucci, Gianna, Vaccari, Gabriele, Acconcia, Filippo, Chiarabelli, Cristiano, Leone, Stefano, Noto, Alessia, Horenkamp, Florian A., Manrique, Santiago, Romeo, Giovanna, Polticelli, Fabio, Geyer, Matthias, Affabris, Elisabetta
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160284/
https://ncbi.nlm.nih.gov/pubmed/21886773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022982
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