HIV-1 Nef Induces Proinflammatory State in Macrophages through Its Acidic Cluster Domain: Involvement of TNF Alpha Receptor Associated Factor 2

BACKGROUND: HIV-1 Nef is a virulence factor that plays multiple roles during HIV replication. Recently, it has been described that Nef intersects the CD40 signalling in macrophages, leading to modification in the pattern of secreted factors that appear able to recruit, activate and render T lymphocy...

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Detalhes bibliográficos
Main Authors: Mangino, Giorgio, Percario, Zulema A., Fiorucci, Gianna, Vaccari, Gabriele, Acconcia, Filippo, Chiarabelli, Cristiano, Leone, Stefano, Noto, Alessia, Horenkamp, Florian A., Manrique, Santiago, Romeo, Giovanna, Polticelli, Fabio, Geyer, Matthias, Affabris, Elisabetta
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160284/
https://ncbi.nlm.nih.gov/pubmed/21886773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022982
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