Policing Parkin with a UblD

Parkin, a ubiquitin ligase of the RING-IBR-RING family, is mutated in familial Parkinsonism. Exciting recent reports transform our thinking of its catalytic activity, and reveal a new autoinhibitory mechanism that is abolished by disease mutations

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Bibliographic Details
Main Authors: Liu, Fen, Walters, Kylie J
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160263/
https://ncbi.nlm.nih.gov/pubmed/21772326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.223
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