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DNA methylation status predicts cell type-specific enhancer activity

Cell-selective glucocorticoid receptor (GR) binding to distal regulatory elements is associated with cell type-specific regions of locally accessible chromatin. These regions can either pre-exist in chromatin (pre-programmed) or be induced by the receptor (de novo). Mechanisms that create and mainta...

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Detalhes bibliográficos
Main Authors: Wiench, Malgorzata, John, Sam, Baek, Songjoon, Johnson, Thomas A, Sung, Myong-Hee, Escobar, Thelma, Simmons, Catherine A, Pearce, Kenneth H, Biddie, Simon C, Sabo, Pete J, Thurman, Robert E, Stamatoyannopoulos, John A, Hager, Gordon L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160184/
https://ncbi.nlm.nih.gov/pubmed/21701563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.210
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