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Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyamines

NMDA receptors (NMDARs) form glutamate-gated ion channels that have central roles in neuronal communication and plasticity throughout the brain. Dysfunctions of NMDARs are involved in several central nervous system disorders, including stroke, chronic pain and schizophrenia. One hallmark of NMDARs i...

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Detalhes bibliográficos
Main Authors: Mony, Laetitia, Zhu, Shujia, Carvalho, Stéphanie, Paoletti, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160180/
https://ncbi.nlm.nih.gov/pubmed/21685875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.203
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