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Cell-to-cell variability of alternative RNA splicing
Heterogeneity in the expression levels of mammalian genes is large even in clonal populations and has phenotypic consequences. Alternative splicing is a fundamental aspect of gene expression, yet its contribution to heterogeneity is unknown. Here, we use single-molecule imaging to characterize the c...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3159976/ https://ncbi.nlm.nih.gov/pubmed/21734645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.32 |
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