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Cell-to-cell variability of alternative RNA splicing

Heterogeneity in the expression levels of mammalian genes is large even in clonal populations and has phenotypic consequences. Alternative splicing is a fundamental aspect of gene expression, yet its contribution to heterogeneity is unknown. Here, we use single-molecule imaging to characterize the c...

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Autors principals: Waks, Zeev, Klein, Allon M, Silver, Pamela A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159976/
https://ncbi.nlm.nih.gov/pubmed/21734645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.32
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