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The Activity of Dispiro Peroxides Against Fasciola hepatica
Dispiro 1,2,4-trioxanes and 1,2,4,5-tetraoxanes had superior efficacy against Fasciola hepatica than the corresponding ozonides (1,2,4-trioxolanes). For highest efficacy, spiroadamantane and carboxymethyl substructures were required. Three compounds completely cured F. hepatica-infected mice at sing...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3159854/ https://ncbi.nlm.nih.gov/pubmed/21802291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.07.024 |
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